Papillary microcarcinoma of the thyroid gland: analysis of prognostic factors including histological subtype.
Eur J Surg Suppl. 2003 Jul;(588):28-32.
Papillary microcarcinoma of the thyroid gland: analysis of prognostic factors including histological subtype.
Falvo L, D'Ercole C, Sorrenti S, D'Andrea V, Catania A, Berni A, Grilli P, De Antoni E.
Division of General Surgery, Department of Surgical Sciences, "La Sapienza" University of Rome, Rome
OBJECTIVE: To evaluate the prognosis of papillary microcarcinoma (PMC) of the thyroid. DESIGN: Prospective study. SETTING: Teaching hospital, Italy. SUBJECTS: 89 patients treated for papillary micro carcinoma of thyroid and followed up for at least 6 years (range 6-12). INTERVENTION: Total thyroidectomy and, for lymph node metastases, laterocervical lymphadenectomy. MAIN OUTCOME MEASURES: Sex distribution, mode of onset of disease, diameter of tumour, histological type, histological stage, presence of lymph node metastases at the time of operation and type of operation. RESULTS: When the disease presented with laterocervical lymph nodes it was histologically more aggressive and included follicular (n = 3) and sclerosing (n = 4) types. CONCLUSION: Papillary microcarcinoma has an excellent prognosis if managed initially by total thyroidectomy.
PMID: 15200040 [PubMed - indexed for MEDLINE]